Please use this identifier to cite or link to this item: http://hdl.handle.net/1946/8755
Mutations in the envelope gene of naturally transmitted maedi-visna virus
In this project, 4 sheep were kept with infected sheep for 3 years. All 4 sheep became infected. Virus was isolated from the sheep, and DNA was isolated from these viruses to observe the mutations that had appeared during this time. We selected a sequence of the Env gene of 560 bp between 7499 and 7981, part of the principal neutralization domain (PND) of the MVV genome. The purpose of this research was to find out how the virus envelope develops in sheep that are infected by natural transmission.