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Please use this identifier to cite or link to this item: http://hdl.handle.net/1946/20635

Title: 
  • c-myc activation in spontaneous rat immunocytomas containing a 6;7 chromosomal translocation
Published: 
  • 1986
Abstract: 
  • In summary, our studies of the rat immunocytoma show that in three different tumors (BL, MPC, RIC) in three different species (human, mouse, rat), nearly identical genetic loci (c-myc, Ig) are juxtaposed via chromosomal translocation. These three tumors represent at least two different stages of B cell maturation, and the natural histories and modes of induction of the tumors are very different. The finding that c-myc/Ig juxtaposition occurs in these three tumors suggests that this configuration plays a central role in the genesis of these B cell tumors.

Citation: 
  • Current Topics in Microbiology and Immunology 1986, 132, 169-174
ISSN: 
  • 0070-217X
Accepted: 
  • Feb 25, 2015
URI: 
  • http://hdl.handle.net/1946/20635


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